The Tufts University Center for Cellular Agriculture (TUCCA) has announced a new scientific paper published in Nature, in which Michael Saad, a PhD student at Tufts University, and his team explain how they created what they claim to be the first and only publicly available fish. Muscle cell lines from Atlantic mackerel.
called continuously Fish muscle cell lines with capacity for myogenic and adipogenic-like phenotypes, study Provides the first spontaneously immortalized fish muscle cell lines for research, ideally serving as a reference for subsequent investigations.
“Here, we established and identified a continuous Atlantic mackerel (scomber scombrus) in skeletal muscle cell lines (“Mac” cells), the report says.
without genetics Engineering
According to TUCCA’s announcement, these cells are immortalized without genetic engineering and can turn into muscle and fat.
“For a field like Cell AG where there is a lack of standardization in research, his Mc1 cell line (and soon to be banked Mc2) is exactly what cultured seafood needs. Think of it as the C2C12 of aquatic cell culture,” added TUCCA.
Includes scientific team of research Michael Saad, John Yuen Jr., Connor Joyce, Jinjin Li, Taihwan Lim, Talia Wolfson, Justin Wu, Jason Laird, Sanjana Visapragada, Olivia Calkins, and Adam Ali.
Recent developments in fish cell lines
- Umami Meat: Last October, the Singaporean company announced that it had filed a patent for its single-stem cell technology that uses mesenchymal stem cell (MSC) lines from fish. This is logic It requires only one cell type and one production line to cultivate muscle and fat, unlike other methods that require multiple production lines and cell types.
- CellQua: This South Korean startup recently emerged, announcing that it has cells from a variety of freshwater and marine species, including zebrafish, Japanese eel, squid, Pacific abalone, Pacific oyster, Japanese flying squid, and white-legged shrimp.
“Cell culture research in aquatic and marine species is relatively understudied when compared to mammalian cell culture research, with zebrafish as an exception.
“Cellular aquaculture has the potential to address fish sourcing concerns by focusing on production efficiency, scaling and controlled farming environments to address food safety concerns. However, to date no fish skeletal muscle cell line has been available to produce cell-cultured fish meat or to use as a model for research, such as immortalized C2C12 mouse myoblasts for mammalian muscle cell culture,” reads the introduction to the report.